What is Mangosteen?
The Mangosteen fruit (or Garcinia mangostana, as it is known scientifically) is exotic, delicious and is packed with xanthones and other phytonutrients that gives impressive health benefits.
What are Xanthones?
Xanthones are biologically active plant phenols found in a few selective tropical plants. There are over 200 xanthones discovered and the mangosteen has over 40.
Xanthones have been found to support and enhance the body's immune system. Xanthones also exhibits strong Antioxidant activity which is beneficial for neutralizing free radicals in the body.
Facts about Xanthones
The Mangosteen has by far the most xanthones of any plant. The pericarp of the mangosteen fruit contains a vast majority of xanthones. Xanthones are some of the most potent antioxidants known. In fact, many doctors refer to xanthones as "super xanthones".
GM-1
GM-1 was discovered by scientists at the Thai Mangosteen Research and Development Centre (TMRDC). It is the most active element amongst the 41 xanthones found in mangosteens.
In cardiovascular diseases, it has been generally accepted that oxidative modification of LDL plays a critical role in atherosclerosis. Therefore, antioxidants able to interfere with lipid per oxidation may be beneficial in reducing atherogenic process. GM-1, was shown for the first time to be a free radical scavenger protecting the LDL from oxidative damage in vitro in 1995. Some years later, a series of GM-1 derivatives were prepared and then tested for their activities on LDL oxidation. Some of them exhibited more profound effects than GM-1 itself. Therefore, some structural modifications of GM-1 are capable of enhancing its antioxidant activity
GM-1 and its derivatives have also been shown to be antiplasmodial, antioxidant and inhibiting eukaryote protein kinases and cyclic nucleotide-binding phosphatase. In some of latest studies the TMRDC scientists had significant results which shed light on how GM-1 acts on the body. It optimizes the immune system to defend infections and hazardous organisms. GM-1 is a safe substance, 5 times safer than citric acid in orange juice. There are no known side effects.
In cardiovascular diseases, it has been generally accepted that oxidative modification of LDL plays a critical role in atherosclerosis. Therefore, antioxidants able to interfere with lipid per oxidation may be beneficial in reducing atherogenic process. GM-1, was shown for the first time to be a free radical scavenger protecting the LDL from oxidative damage in vitro in 1995. Some years later, a series of GM-1 derivatives were prepared and then tested for their activities on LDL oxidation. Some of them exhibited more profound effects than GM-1 itself. Therefore, some structural modifications of GM-1 are capable of enhancing its antioxidant activity
GM-1 and its derivatives have also been shown to be antiplasmodial, antioxidant and inhibiting eukaryote protein kinases and cyclic nucleotide-binding phosphatase. In some of latest studies the TMRDC scientists had significant results which shed light on how GM-1 acts on the body. It optimizes the immune system to defend infections and hazardous organisms. GM-1 is a safe substance, 5 times safer than citric acid in orange juice. There are no known side effects.
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